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. 2017 Aug 25;7:9422. doi: 10.1038/s41598-017-09744-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Connectivity results between regions of interest (ROI) in the default mode network and the task-positive network. Associations between time courses from each ROI were determined for each run and entered into a mixed-effects model. Thus, the intercept represents the overall association between nodes; sleep deprivation represents the main effect of sleep deprivation vs full sleep; age group represents the main effect of older vs younger age group membership; and the sleep-age group interaction represents the interaction effect of sleep deprivation and older age. β is the standardized regression coefficient. False discovery rate correction was performed within each of the four sets of comparisons, and node pairs where p _FDR < 0.05 are indicated with an asterisk (*).