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. 2017 Aug 25;7:9481. doi: 10.1038/s41598-017-10169-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Heat map indicating the cytotoxic effects of whole materials according to concentration and time. The colors indicate the relative cytotoxicity levels (percentages of hemolysis, cell death, and apoptotic or necrotic cells) for each polymer and combination under 64 different conditions in the rows (all polymers and combinations of three/five doses × four culture times × three assays).