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. 2017 Aug 11;174(18):3081–3093. doi: 10.1111/bph.13942

Figure 2.

Figure 2

Effects of dofetilide and its derivatives Dofe54 and Dofe33 on AP characteristics in hiPSC‐CMs. Representative AP recordings of hiPSC cardiomyocytes after incubating with dofetilide, n = 4–5 (A), the high affinity derivative Dofe54, n = 4 (B) and the low affinity derivative Dofe33, n = 4 (C) and plots of APD90 as % of control versus concentrations of dofetilide, n = 4–5 (D), Dofe54, n = 4 (E) and Dofe33, n = 4 (F). The data points represent the mean ± SEM (see Table 1) and were fitted by a Hill equation for dofetilide and Dofe54. The data points for Dofe33 were connected by lines.