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. 2017 Aug 11;174(18):3045–3057. doi: 10.1111/bph.13934

Table 2.

Differential leukocyte counts in the BALF of mice at 28 days in therapeutic model

Neutrophils (×106) Macrophages (×106) Lymphocytes (×106)
Sham 0.00 ± 0.00* 0.18 ± 0.01* 0.00 ± 0.00*
Bleomycin 0.30 ± 0.02 0.60 ± 0.02 0.10 ± 0.00
AQX‐1125 3 mg·kg−1 0.28 ± 0.02 0.54 ± 0.02* 0.09 ± 0.00*
AQX‐1125 10 mg·kg−1 0.13 ± 0.01* 0.39 ± 0.01* 0.05 ± 0.00*
AQX‐1125 30 mg·kg−1 0.05 ± 0.00* 0.26 ± 0.01* 0.03 ± 0.00*
Pirfenidone 90 mg·kg−1 0.05 ± 0.00* 0.25 ± 0.01* 0.03 ± 0.00*

Data are the mean ± SEM of the absolute leukocyte counts (×106 cells) (n = 10–29).

*

P < 0.05 shows a significant effect of AQX‐1125 or pirfenidone, compared to the vehicle‐treated bleomycin group.