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. 2017 Aug 21;11:152. doi: 10.3389/fnbeh.2017.00152

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Copyright © 2017 Gamsby, Pribish, Stevanovic, Yunus and Gulick.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of overall changes in alcohol and water intake during baseline alcohol access and 18HR environmental CD. Mice in CD drank significantly more alcohol than controls in the total 24-h cycle of 18HR photoperiods (ignoring light and dark; A). Although alcohol preference increased over time (B) there was no effect of CD and the increase was due to a significant decrease in water intake in both groups (C) (data indicate the mean ± SEM for n = 6; asterisks indicate significant differences between control and CD groups).