Table 2. Additional intervention model parameters, with distributions and sources.
| Parameter | Distribution | Mean (with standard deviation) or range or confidence interval (CI) | Source |
|---|---|---|---|
| Effects | |||
| Reduction in vector population, medium technology vector control | Uniform | 50–70% | (8)(31) |
| Reduction in vector population, high technology vector control | Uniform | 70–90% | |
| Outbreak length (weeks), sustained vector control and/or outbreak response | Uniform | 1–2 | Conservative assumption relative to [30] |
| Immunization coverage (annual) | Uniform | Country-specific |
Minimum is 9–14 year-old population in first year of implementation (7.8–12.9% of total population in the six countries); 9 year-old population thereafter (1.3–2.2%); up to a maximum of 80% of seropositive and susceptible population |
| Vaccine efficacy (seropositive) | Beta | 82% (95% CI 67–90%) |
[55], pooled result for ≥ 9 years of age; we assume that 100% of those vaccinated in any given year are seropositive |
| Costs | |||
| Sustained vector control (per person per month, 2013 US$) | Lognormal | Country-specific | See Table 3 |
| Vector control during outbreak only (per person per week, 2013 US$) | Triangular | Country-specific | [53], with adjustments using proportion of labour in costs and GDP per capita to determine the minimum, maximum and most likely values |
| Surveillance for vector control (per person per week, 2013 US$) | Triangular | Country-specific | [56], with adjustments using proportion of labour in costs and GDP per capita to determine the minimum, maximum and most likely values |
| Immunization (per person immunized, 2013 US$) | Deterministic | 20 | Conservative assumption |