Table 4.

Sex-specific associations of individual metabolites with MetRisk z-score among 238 ELEMENT adolescents.

	β (95% CI) MetRisk z score per 1 unit increment in metabolite z score
	Unadjusted	Model 1	Model 2
Girls (n = 125)
Diacylglycerol 16:0/16:0	0.63 (0.49, 0.76)	0.61 (0.47, 0.75)	0.60 (0.47, 0.74)
1,3-dielaidin	0.51 (0.36, 0.66)	0.49 (0.35, 0.64)	0.49 (0.35, 0.63)
Myo-inositol	0.44 (0.28, 0.59)	0.43 (0.27, 0.58)	0.43 (0.27, 0.58)
Urate	0.44 (0.27, 0.61)	0.42 (0.25, 0.58)	0.40 (0.23, 0.56)
Thymine	−0.33 (−0.49, −0.17)	−0.38 (−0.54, −0.22)	−0.39 (−0.55, −0.23)
Dodecenedioic acid	−0.33 (−0.47, −0.17)	−0.34 (−0.49, −0.19)	−0.35 (−0.50, −0.20)
N-acetylglycine	−0.42 (−0.58, −0.25)	−0.51 (−0.68, −0.35)	−0.53 (−0.69, −0.36)
Boys (n = 113)
Diacylglycerol 16:0/16:0	0.42 (0.27, 0.57)	0.43 (0.29, 0.58)	0.42 (0.28, 0.56)
Tyrosine	0.37 (0.21, 0.53)	0.35 (0.19, 0.50)	0.33 (0.17, 0.48)
5′-methylthioadenosine (MTA)	0.30 (0.15, 0.46)	0.35 (0.20, 0.49)	0.32 (0.18, 0.46)

Model 1: Adjusted for maternal education level and child’s age.

Model 2: Model 1 + pubertal status.

Bolded estimates indicate statistical significance at P <0.05.