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. 2017 Jul 5;8(4):e00944-17. doi: 10.1128/mBio.00944-17

FIG 1 .

FIG 1 

Trex1 and Aim2 double knockdown induces a type I IFN response in macrophages. IFN-β, CXCL10, Trex1, and Aim2 RNA levels upon knockdown of the genes indicated in NR9456 cells (A) and BMDMs (B). RNA were analyzed by RT-qPCR. The values presented are normalized to Gapdh and are the mean ± the standard error of the mean of three experiments. *, P < 0.05; **, P < 0.005; ***, P < 0.0005 (two-tailed t test). The knockdown of TREX1 and AIM2 protein levels by siRNA treatment is shown in Fig. S2B. siCont, control siRNA.