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Aim2 and Trex1 depletion increases ISG RNA levels. A PCR array of NR9456 cells was conducted after knocking down the genes indicated. (A) Scatterplot of the genes analyzed. (B) Heat map of genes with significant differences from those of control siRNA (siCont)-treated cells. Equal amounts of total RNAs from three different experiments were combined and subjected to cDNA synthesis. A single PCR array was performed.
