Fig. 3.

Effects of treatment with Hsp70 siRNA and cisplatin on cell viability. The cells were treated with control or Hsp70 siRNA for 48 h and were then treated with cisplatin (CDDP) at the indicated concentrations for 48 h. Cell viability was determined using the RealTime-Glo MT Cell Viability Assay (a). IC₅₀ values were determined after 48-h exposure to cisplatin (b). Values for Hsp70-silenced cells were compared to those of control siRNA-administered cells treated with the same concentration of cisplatin. The data are expressed as mean ± standard deviation (n = 5). *p < 0.05; **p < 0.01