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. 2017 Aug 24;8:1013. doi: 10.3389/fimmu.2017.01013

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Copyright © 2017 Li, Zhao, Li, Zheng, Liu, Jiang, Zhang and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Downregulation of LILRB4 on human decidual macrophages infected with Toxoplasma gondii. Changes in the expression of M1 and M2 membrane-functional molecules. Histograms of flow cytometry in uninfected, infected, and LILRB4-neutralized and infected human decidual macrophage are presented. Representative histograms of M2 membrane-functional molecules: CD163 (E,F), CD209 (G,H), and CD206 (I,J). Representative histograms of M1 membrane-functional molecules CD80 (A,B) and CD86 (C,D). (K) M1/M2 ratios (CD86/CD163, CD86/CD209, CD86/CD206, CD80/CD163, CD80/CD209, and CD80/CD206) for uninfected, infected, and LILRB4-neutralized and infected human decidual macrophages. Representative data were from one individual for uninfected, infected and LILRB4-neutralized and infected groups, respectively. Data are presented as means ± SD (*p < 0.05, **p < 0.01); nine human spontaneous abortion specimens were assayed for each group and were compared by unpaired t-tests.