Table 2.

Clusters of GM alterations shown by the VBM analysis using VBM8 versus CAT12.

	Analysis	Location of peak voxels	Hemisphere	Cluster size (no of voxels)	Talairach coordinates (x, y, z)	MNI coordinates (x, y, z)	T-value (peak voxel)
VBM8	(a) HC > LTLE-HS	–	–	–	–	–	–
	(b) HC > RTLE-HS	Hippocampus	R	110	31 −21 −8	33 −19 −14	6.30
	(c) RTLE-no > HC	Amygdala	R	935	25 −11 −10	26 −9 −17	7.21
CAT12	(a) HC > LTLE-HS	Hippocampus	L	1,281	−26 −18 −11	−27 −16 −18	7.93
	(b) HC > RTLE-HS	Hippocampus	R	2,201	27 −28 −2	28 −27 −8	10.36
	(c) RTLE-no > HC	Amygdala	R	1,256	29 −5 −19	30 −2 −27	4.8

Anatomical regions were derived from the Talairach Client program.

L, heft hemisphere; R, right hemisphere; MNI, Montreal Neurological Institute (FWE-corrected at p < 0.05); GM, gray matter; HC, healthy control; VBM, voxel-based morphometry; FEW, family-wise error.