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RAISE study design aIrinotecan: 180 mg/m2; Folinic acid: 400 mg/m2; 5-flurouracil: 400 mg/m2 bolus followed by 400 mg/m2 given as a continuous infusion over 48 hours FOLFIRI, folinic acid, 5-fluorouracil, and irinotecan; IG immunogenicity; IV intravenous; ORR objective response rate; PFS progression-free survival; PK pharmacokinetics; PRO patient-reported outcomes; RAM ramucirumab
