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. 2017 Jul 25;80(3):599–608. doi: 10.1007/s00280-017-3380-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — a RAISE overall survival by ramucirumab C_min,ss exposure quartile. Ramucirumab C_min,ss quartile concentrations: Q1 (<25%) <49.7 µg/mL, Q2 (25% to <50%) 49.7 to <62.6 µg/mL, Q3 (50% to <75%) 62.6 to <81.1 µg/mL, Q4 (≥75%) ≥81.1 µg/mL. b RAISE progression-free survival by ramucirumab C_min,ss exposure quartile. Ramucirumab C_min,ss quartile sconcentrations: Q1 (<25%) <49.7 µg/mL, Q2 (25% to <50%) 49.7 to <62.6 µg/mL, Q3 (50% to <75%) 62.6 to <81.1 µg/mL, Q4 (≥75%) ≥81.1 µg/mL C_min,ss, minimum concentration at steady state; PBO placebo; Q quartile; RAM ramucirumab