Figure 4.

Prognostic value of changes in the protein panel score from diagnosis to after initiation of therapy

(A) Cox proportional hazard estimates associated with changes in individual proteins and the overall panel score, showing only the combination of proteins into the score is significantly associated with outcomes. (B) Kaplan–Meier survival estimates in patients with serial panel score measurements (cohort 3), showing an increase in the panel score from diagnosis to after initiation of therapy is associated with poor outcomes.