Figure 4.

Number of cells in the SGZ of the dentate gyrus expressing the proliferation marker Ki67 in wild-type (WT) and aphakia (ak/ak) mice under control conditions (CTR) and after seven days of voluntary exercise in a running wheel (RUN; bars indicate mean values ± SEM). Two-way ANOVA with post-hoc t-test and Bonferroni adjustment with genotype and runner group as fixed factors revealed that genotype and runner group have nosignificant interaction effect on Ki67-positive cell numbers (p = 0.881, F = 0.02) and no significant differences among genotypes (p = 0.160, F = 2.4), but significant differences between runners and controls (p = 0.002, F = 19.7); ^*p < 0.05 from Bonferroni-adjusted post-hoc t-test; n = 3).