Table 1.
Demographics of HCV patients on methadone maintenance.
| Demographic | mDOT | SAT |
|---|---|---|
| Number of subjects | 12 | 9 |
| Mean age (range) in years | 40 (29–51) | 43 (36–54) |
| Gender | ||
| Female | 7 | 3 |
| Male | 5 | 6 |
| Race/ethnicity | ||
| African-American | 1 | 1 |
| Hispanic | 0 | 3 |
| Caucasian | 11 | 5 |
| Mean (range) years of nonconsecutive opioid use | 8 (1–25) | 15 (3–37) |
| Mean (range) duration of current methadone maintenance (months) | 140 (1–36) | 149 (7–29) |
| Genotype | ||
| 1, 4 | 8 | 6 |
| 2, 3 | 4 | 3 |
| Biopsy staging (only GT 1,4) | ||
| 2 | 4 | 4 |
| 3 | 2 | 0 |
| 4 | 2 | 2 |
| HIV coinfection | 3 | 3 |
| Depressive disorders | 8 | 5 |
| Anxiety disorders | 8 | 3 |
| Diagnostic and Statistical Manual of Mental Disorders-IV criteria for alcohol abuse/dependence | 4 | 2 |
| Diagnostic and Statistical Manual of Mental Disorders-IV criteria for cocaine abuse/dependence | 9 | 7 |
| Positive cocaine urine toxicology in 30 days prior to study enrollment | 3 | 4 |
Note: HCV, hepatitis C virus; GT, genotype; mDOT, modified directly observed therapy; SAT, self-administered therapy.