Table 8.
Extrolites found in the different species of Aspergillus section Aspergillus. Tetracyclic means compounds with a UV spectrum typical of BMS-192548 (Shu et al. 1995) or similar UV spectra.
| Species | Extrolites |
|---|---|
| Aspergillus aerius | Auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, tetracyclic, tetrahydroauroglaucin |
| A. appendiculatus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin, “MYO” |
| A. aurantiacoflavus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin |
| A. brunneus | Asperflavin, asperentins, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, 5-farnesyl-5,7-dihydroxy-4-methylphthalide, erythroglaucin, flavoglaucin, isoechinulins, mycophenolic acid, neoechinulins, physcion, questin, tetracyclic, tetrahydroauroglaucin |
| A. caperatus | Auroglaucin, a bisanthron, dihydroauroglaucin, echinulins, epiheveadrides, flavoglaucin, isoechinulins, neoechinulins, physcion, tetrahydroauroglaucin |
| A. chevalieri | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin, unique: “MYO” |
| A. cibarius | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, erythroglaucin, flavoglaucin, neoechinulins physcion, tetracyclic, tetrahydroauroglaucin |
| A. costiformis | Auroglaucin, dihydroauroglaucin, echinulins, epiheveadrides, flavoglaucin, isoechinulins, neoechinulins, physcion, tetrahydroauroglaucin |
| A. cristatus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, tetrahydroauroglaucin, “MYO” |
| A. cumulatus | Auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, tetracyclic, tetrahydroauroglaucin (DTO 308-D8: “canescins”; DTO 355-G9 produces another type of indolealkaloids than echinulins in addition to echinulins, similar to 12,13-dehydro-deoxybrevianamide E) |
| A. endophyticus | Auroglaucin, bisanthrones, dihydroauroglaucin, echinulins (for all species we did find preechinulin, echinulin, neoechinulin A and B), emodin, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, tetrahydroauroglaucin |
| A. glaucus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides (traces), erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin |
| A. intermedius | Asperflavin, auroglaucin, dihydroauroglaucin, echinulins, epiheveadrides, flavoglaucin, isoechinulins, LL-S491β, neoechinulins, physcion, questin, tetrahydroauroglaucin |
| A. leucocarpus | An apolar indoloterpene, echinulins, epiheveadrides, neoechinulins, “MUDI” 1-3 |
| A. levisporus | Auroglaucin, dihydroauroglaucin, echinulins, flavoglaucin, isoechinulins, neoechinulins, tetrahydroauroglaucin, unique: “WOF” 1 & 2 |
| A. mallochii | Auroglaucin, dihydroauroglaucin, echinulins, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, tetracyclic, tetrahydroauroglaucin |
| A. megasporus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulin, emodin, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, preechinulin, physcion, quinolactacin (A1, A2, B), tetracyclic, tetrahydroauroglaucin |
| A. montevidensis | Apolar indoloterpenes, asperflavin in few isolates, auroglaucin, dihydroauroglaucin, echinulins, epiheveadrides, flavoglaucin, isoechinulins, neoechinulins, tetrahydroauroglaucin |
| A. neocarnoyi | Asperentins, asperflavin, auroglaucin, a bisanthron, dihydroauroglaucin, echinulins, flavoglaucin, neoechinulins, questin, questinol, tetracyclic, tetrahydroauroglaucin |
| A. niveoglaucus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, erythroglaucin, flavoglaucin, mycophenolic acid (tentatively identified), neoechinulins, physcion, questin, questinol, siderin (in DTO 355-C4), tetracyclic, tetrahydroauroglaucin |
| A. osmophilus | Asperflavin, auroglaucin, flavoglaucin, dihydroauroglaucin, tetrahydroauroglaucin, echinulin and neoechinulin A. |
| A. porosus | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, isoechinulins, flavoglaucin, neoechinulins, physcion, tetrahydroauroglaucin |
| A. proliferans | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, tetracyclic, tetrahydroauroglaucin |
| A. pseudoglaucus | Asperentins, asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, erythroglaucin, 6-farnesyl-5,7-dihydroxy-4-methylphthalide, flavoglaucin, isoechinulins, mycophenolic acid, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin |
| A. ruber | Auroglaucin, bisanthrons, catenarin, dihydroauroglaucin, echinulins, epiheveadrides, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, physcion, questin, questinol, tetracyclic, tetrahydroauroglaucin (Ex type of A. athecius CBS 464.65 produced breviones and no red anthraquinones) |
| A. sloanii | Auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, flavoglaucin, physcion, tetracyclic, tetrahydroauroglaucin |
| A. tamarindosoli | Asperflavin, auroglaucin, bisanthrons, echinulins, emodin, dihydroauroglaucin, epiheveadrides, flavoglaucin, isoechinulins, neoechinulins, physcion, tetrahydroauroglaucin, unique: “MYO” |
| A. teporis | Echinulins, epiheveadrides, isoechinulins, neoechinulins, unique: “KYF” 1 & 2 |
| A. tonophilus | Auroglaucin, bisanthrons (few), dihydroauroglaucin, echinulins, flavoglaucin, an apolar indoloterpene, isoechinulins, neoechinulins, tetrahydroauroglaucin |
| A. xerophilus | Bisanthrons, dihydroauroglaucin, echinulins, erythroglaucin, isoechinulins, neoechinulins, physcion, sulochrin, tetracyclic, unique: “XERO” |
| A. zutongqii | Asperflavin, auroglaucin, bisanthrons, dihydroauroglaucin, echinulins, emodin, epiheveadrides, erythroglaucin, flavoglaucin, isoechinulins, neoechinulins, (tetracyclic), tetrahydroauroglaucin |