Table 1.
Demographic data of overall study participants
| Category | Adequate folate status (n = 100) | Low folate status (n = 57) | p |
|---|---|---|---|
| Age (years) | 18 (15–18.8) | 17.7 (15–18.9) | NS |
| Gynecological age (years) | 4.9 (1.0–9.6) | 5.0 (2.0–9.1) | NS |
| Ethnicity n (%) | |||
| Caucasian | 69 (69%) | 33 (57.9%) | NS |
| Other | 31 (31%) | 24 (42.1%) | N |
| Primiparous n (%) | 94 (94%) | 56 (98.2%) | NS |
| Smoking status n (%) | |||
| Smoker | 31 (31%) | 24 (42.1%) | NS |
| Non‐smoker | 69 (69%) | 33 (58.9%) | NS |
| BMI (kg/m2) | 22.5 (14.8–42.3) | 22.3 (15.4–40.8) | NS |
| Gestation at delivery (weeks) | 40.1 (35.9–42.0) | 40.3 (36.0–43.1) | NS |
| Birthweight (g) | 3300 (2020–4460) | 3200 (2000–4160) | NS |
| Individualized birthweight centile (IBC) | 40 (0–99) | 28 (0–98) | 0.05 |
| Male infant n (%) | 45 (45%) | 27 (47.5%) | NS |
| Serum folate (nmol/L) | 14.7 (2.7–51.0) | 7.7 (3.4–17.0) | <0.0001 |
| RBC folate (nmol/L) | 948.3 (455.5–1602.1) | 385.2 (219.8–449.0) | <0.0001 |
Data are median (range).Mann–Whitney or Fisher's exact test.
RBC, red blood cell.