Table 1.
Cartilage oligomeric matrix protein neoepitopes released from articular cartilage explants stimulated with interleukin‐1β (IL‐1) using mass spectrometry and relative quantification with isobaric tandem mass tags. The relative amount (ratio of peptides versus reference pool) of peptides in culture media of unstimulated (control) and IL‐1 stimulated explants are given at different time points
| Peptide sequence | Mascot ion score | Position Q9BG80_HORSE | IL‐1/Control Day 3 | IL‐1/Control Day 6 | IL‐1/Control Day 9 | IL‐1/Control Day 12 | IL‐1/Control Day 15 | IL‐1/Control Day 18 | IL‐1/Control Day 22 |
|---|---|---|---|---|---|---|---|---|---|
| Y↓SGPTHEGVGMAFAK | 56 | 156↓157 | 2.342 | 2.216 | 1.773 | 2.080 | 1.175 | 1.328 | 2.203 |
| G↓SFQCGPCQPGFVGDQASGCRPR | 36 | 200↓201 | 1.774 | 1.853 | |||||
| DVDHDFVGDACDSDQD↓K | 81 | 433↓434 | 2.433 | 1.397 | 0.000 |