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. 2017 Aug 28;37(18):e00125-17. doi: 10.1128/MCB.00125-17

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Copyright © 2017 Kondo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — JHDM1D-AS1 knockdown decreased tumorigenicity in vivo. (A) Knockdown efficiency of siRNA against JHDM1D-AS1 in vitro. (B) JHDM1D-AS1 knockdown does not affect cell growth in the control medium in PANC-1 and AsPC-1 cells. (C) JHDM1D-AS1 knockdown does not affect cell growth under nutrient starvation in PANC-1 and AsPC-1 cells. (D) Depletion of JHDM1D-AS1 by siRNA in PANC-1 and PANC1 cells suppresses tumor growth in vivo. The expression of each transcript is reported relative to that of β-actin and was determined by real-time qPCR analysis. Student's t tests were performed for the indicated comparisons (*, P < 0.05; ***, P < 0.005).