Table 1.
MONICA1 | DCH | Inter99 | |
---|---|---|---|
N | 1257 | 2165 | 3606 |
Follow-up time (years) | 5.0 (4.9; 5.3) | 5.3 (5.0; 5.8) | 5.4 (5.1; 5.7) |
Dietary variables | |||
Alcohol intake (drinks/day) | 1.0 (0.0; 5.0) | 1.0 (0.0; 5.4) | 0.8 (0.0; 4.3) |
Energy (MJ/d) | 9.0 (5.1; 14.9) | 8.8 (5.3; 14.3) | 9.4 (5.2; 15.8) |
BW (kg) | |||
Baseline (kg) | 69.0 (52.0; 93.0) | 77.1 (56.8; 104.4) | 75.2 (54.9; 102.4) |
Follow-up (kg) | 69.9 (51.4; 94.7) | 82.0 (58.0; 110.0) | 76.0 (55.5; 103.5) |
ΔBW (kg/year) | 0.2 (−1.0; 1.6) | 1.0 (−1.1; 2.4) | 0.2 (−1.4; 1.7) |
WC (cm) | |||
Baseline (cm) | - | 90.0 (70.0; 112.0) | 84.0 (67.0; 105.0) |
Follow-up (cm) | - | 98.0 (76.0; 121.0) | 87.0 (69.0; 109.0) |
ΔWC (cm/year) | - | 1.4 (−0.8; 4.4) | 0.5 (−1.3; 2.5) |
WC BMI (cm) | |||
Baseline (cm) | - | −0.3 (−7.9; 9.1) | −0.2 (−7.7; 8.5) |
Follow-up (cm) | - | −0.2 (−11.5; 12.6) | −0.2 (−8.2; 9.1) |
ΔWCBMI (cm/year) | - | −0.0 (−2.0; 2.2) | 0.0 (−1.4; 1.2) |
SNP-based variables 2 | |||
BMI score | 29 (23;35) | 28 (23; 35) | 29 (23; 34) |
WC score | 3 (1; 6) | 3 (1; 6) | 3 (1; 6) |
WHRBMI score | 14 (10; 18) | 14 (10; 18) | 14 (10; 18) |
Complete score | 44 (37; 52) | 44 (37; 51) | 44 (36; 51) |
Covariates | |||
Age, baseline (years) | 41.4 (30.6; 61.1) | 53.0 (50.0; 58.0) | 45.0 (34.7; 59.8) |
Height (cm) | 169.0 (156.0; 184.0) | 171.0 (157.5; 186.0) | 172.0 (158.0; 187.5) |
Gender, female (%) | 52.1 | 49.4 | 51.4 |
Smoking, never smokers (%) | 30.1 | 41.4 | 40.8 |
Education, ≤primary school (%) | 34.5 | 30.2 | 24.9 |
Physical activity, most sedentary group (%) | 21.6 | 9.5 | 11.2 |
Menopausal status, post-menopausal (%) | 41.7 | 55.6 | 25.9 |
Abbreviation: Body Mass Index (BMI), Body Weight (BW), Waist Circumference (WC), Waist-Hip-Ratio (WHR)
1Results presented as median (5–95 percentiles) unless otherwise stated
1Information on WC was not available in the MONICA cohort
2Sum of BMI, WC or WHR associated risk alleles. In MONICA: n = 941 on BMI score, n = 1185 on WC score, n = 1121 on WHR-score, n = 836 on complete score. In DCH: n = 1438 on BMI score, n = 1805 on WC score, n = 1624 on WHR-score, n = 1247 on complete score. In Inter99: n = 2211 on BMI-score, n = 2995 on WC score, n = 2903 on WHR score, n = 1837 on complete score