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. 2017 Aug 25;19:193. doi: 10.1186/s13075-017-1404-z

Table 2.

Comparison of IFN-γ releasing assay (IGRA) results in patients with active and inactive SLE

Variables Active SLE (n = 64) Inactive SLE (n = 54) p value
IGRA results, n (%)
 Positive 4 (6.2) 9 (16.6) 0.073
 Negative 31 (48.4) 45 (83.3) <0.001
 Indeterminate 29 (45.3) 0 (0.0) <0.001
IFN-γ level (IU/mL)
 Nil (IU/mL) 0.45 (2.00) 0.09 (0.05) <0.001
 Tuberculosis antigen (IU/mL) 0.43 (1.61) 0.12 (0.21) 0.028
 Mitogen (IU/mL) 2.93 (7.09) 11.15 (5.03) <0.001
 Ex vivo IFN-γ production (IU/mL)a 0.92 (4.93) 11.06 (5.27) <0.001

Values are expressed as the median (interquartile range) or number (percentage)

IFN-γ interferon gamma, IGRA IFN-γ-releasing assay

aEx vivo IFN-γ production was estimated by calculating the difference in IFN-γ production between the mitogen tube and the nil tube (mitogen minus nil)