Table 3.
Model used | Parameter estimated | Sanderson et al. | Duncan et al. | Payne et al. | SD across studies fixed/non-fixed intercept model | |||
---|---|---|---|---|---|---|---|---|
Fixed intercept (n = 5) | Non-fixed intercept (n = 5) | Fixed intercept (n = 8) | Non-fixed intercept (n = 8) | Fixed intercept (n = 27) | Non-fixed intercept (n = 27) | |||
Log-linear |
m (SE) [95% CI] |
0.63 (0.025) [0.58–0.68] |
0.67 (0.084) [0.50–0.84] |
0.53 (0.013) [0.50–0.55] |
0.69 (0.055) [0.58–0.80] |
0.52 (0.010) [0.50–0.54] |
0.66 (0.024) [0.61–0.71] |
0.061/0.017 |
Sine-wave (fixed period) |
m (SE) [95% CI] |
0.63 (0.024) [0.58–0.67] |
0.67 (0.083) [0.51–0.83] |
0.53 (0.015) [0.50–0.56] |
0.74 (0.036) [0.67–0.81] |
0.52 (0.010) [0.50–0.54] |
0.68 (0.022) [0.63–0.72] |
0.059/0.040 |
Sine-wave (non-fixed period) |
m (SE) [95% CI] |
0.62 (0.024) [0.58–0.67] |
0.71 (0.068) [0.58–0.84] |
0.53 (0.016) [0.50–0.56] |
0.73 (0.035) [0.66–0.80] |
0.67 (0.014) [0.65–0.70] |
0.70 (0.015) [0.67–0.72] |
0.071/0.018 |
Fixed-intercept models had the intercept fixed to the inoculum size, whereas non-fixed-intercept models estimated the intercept as part of model fitting. Sine-wave models were fitted either with the period fixed to 48 h (fixed period), or with the period not fixed (non-fixed period). The parasite growth rate estimate (m) overall by study was estimated by the mixed effects model
m parasite growth rate estimate, SD standard deviation, SE standard error, CI confidence interval