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. 2017 Aug 25;16:352. doi: 10.1186/s12936-017-1999-1

Table 3.

Parasite growth rate estimates for models fitted overall by study using mixed effects models (models 7–12)

Model used Parameter estimated Sanderson et al. Duncan et al. Payne et al. SD across studies fixed/non-fixed intercept model
Fixed intercept (n = 5) Non-fixed intercept (n = 5) Fixed intercept (n = 8) Non-fixed intercept (n = 8) Fixed intercept (n = 27) Non-fixed intercept (n = 27)
Log-linear m (SE)
[95% CI]
0.63 (0.025)
[0.58–0.68]
0.67 (0.084)
[0.50–0.84]
0.53 (0.013)
[0.50–0.55]
0.69 (0.055)
[0.58–0.80]
0.52 (0.010)
[0.50–0.54]
0.66 (0.024)
[0.61–0.71]
0.061/0.017
Sine-wave (fixed period) m (SE)
[95% CI]
0.63 (0.024)
[0.58–0.67]
0.67 (0.083)
[0.51–0.83]
0.53 (0.015)
[0.50–0.56]
0.74 (0.036)
[0.67–0.81]
0.52 (0.010)
[0.50–0.54]
0.68 (0.022)
[0.63–0.72]
0.059/0.040
Sine-wave (non-fixed period) m (SE)
[95% CI]
0.62 (0.024)
[0.58–0.67]
0.71 (0.068)
[0.58–0.84]
0.53 (0.016)
[0.50–0.56]
0.73 (0.035)
[0.66–0.80]
0.67 (0.014)
[0.65–0.70]
0.70 (0.015)
[0.67–0.72]
0.071/0.018

Fixed-intercept models had the intercept fixed to the inoculum size, whereas non-fixed-intercept models estimated the intercept as part of model fitting. Sine-wave models were fitted either with the period fixed to 48 h (fixed period), or with the period not fixed (non-fixed period). The parasite growth rate estimate (m) overall by study was estimated by the mixed effects model

m parasite growth rate estimate, SD standard deviation, SE standard error, CI confidence interval