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. 2017 Aug 25;16:143. doi: 10.1186/s12943-017-0714-8

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Characterization of normoxic and hypoxic exosomes derived from bladder cancer 5637 cells. a Transmission electron microscopy images of exosomes derived from normoxic and hypoxic 5637 cells. b Nanoparticle tracking analysis were analyzed the size distribution of normoxic and hypoxic exosomes derived from 5637 cells. c Western blotting analysis for exosomal markers TSG101, CD63, Hsp70 and Hsp90 of normoxic and hypoxic exosomes derived from 5637 cells; Equal amount of normoxic or hypoxic exosomes (500 ng) were used for western blotting analysis