Figure 4. The effects of JDTic on AA-induced stretching and CPA.
The effects of subcutaneous JDTic (10 mg/kg) pretreatment to vehicle, acetic acid (AA, 1%, intraperitoneal) and U,50488H (10 mg/kg) administrations on (A) AA-induced stretching and (B) conditioned place aversion (CPA). Vehicle was saline for test drugs and sterile water for AA. Data are expressed as means ± S.E.M. from 5–9 mice. * indicates a significant effect compared to correspondent vehicle by one-way ANOVA followed by Tukey’s post hoc test (*p<0.05). #indicates a significant effect compared to U50,488H by one-way ANOVA followed by Tukey’s post hoc test (#p<0.05).