Figure 3.

Blood pressure (A), wall displacement (B), and the resulting ISF pressure (C) in the MCA. Simulations were performed using the VaMpy Python package (Diem and Bressloff, 2016) and the simulation parameters are listed in Table 2. Wall stiffness is high in small blood vessels, therefore pressure gradients in time are steep. Wall displacement was calculated from the linear elasticity approximation derived in Supplementary Material 2. The input function R_i(z, t) to the BM model Equation (6) is obtained by adding the radius at rest a (see geometry depiction in Figure 1).