Table 1. Characteristics of the 38 patients with IPF.
| Variables | Values | Variables | Values | |
|---|---|---|---|---|
| Gender (male/female, n) | 26/12 | TRPG (mmHg) | 24.5 ± 8.8 | |
| Age (years) | 71.3 ± 8.4 | Pulmonary function | ||
| Body mass index (kg/m2) | 23.9 ± 3.0 | VC (%) | 89.5 ± 19.7 | |
| Time since diagnosis (months) | 59.4 ± 59.3 | FVC (%) | 88.2 ± 19.6 | |
| Dyspnea | FEV1 (%) | 98.9 ± 20.0 | ||
| MRC grade (0 to 4) | 1.0 ± 0.7 | DLCO (%) | 47.8 ± 17.0 | |
| BDI | 8.0 ± 2.7 | HADS score | ||
| Treatment | Anxiety | 4.2 ± 3.3 | ||
| LTOT, n (%) | 5 (13.2) | Depression | 5.5 ± 3.3 | |
| Pirfenidone, n (%) | 15 (40.0) | Quadriceps force (Nm) | 97.8 ± 43.5 | |
| Oral corticosteroids, n (%) | 6 (15.8) | 6MWT | ||
| Blood gas data | 6MWD (m) | 443.8 ± 98.5 | ||
| PaO2 (mmHg) | 80.8 ± 15.3 | Lowest SpO2 (%) | 89.9 ± 4.3 | |
| PaCO2 (mmHg) | 39.1 ± 7.4 | Highest HR (%) | 110.8 ± 17.5 | |
| Serum marker | Dyspnea | 2.8 ± 1.7 | ||
| SP-D (ng/ml) | 190.3 ± 129.6 | Leg fatigue | 1.9 ± 1.7 | |
| KL-6 (U/ml) | 893.2 ± 397.2 | PA (steps/day) | 5,148.4 ± 3,295.7 |
Values are mean ± SD unless otherwise stated.
BDI: Baseline Dyspnea Index; DLCO: diffusion capacity of carbon monoxide; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; HADS: hospital anxiety and depression scal; HR: heart rate; KL-6: Krebs von den Lungen-6; LTOT: long-term oxygen therapy; MRC: Medical Research Council; PA: physical activity; PaCO2: partial pressure of carbon dioxide in arterial blood; PaO2: partial pressure of oxygen in arterial blood; SP: surfactant protein; SpO2: oxygen saturation; TRPG: tricuspid regurgitation pressure gradient; VC: vital capacity; 6MWT: 6-minute walk test; 6MWD: 6-minute walk distance