Table 1.
Baseline clinical and biochemical characteristics of study subjects by obesity and insulin sensitivity status
| Characteristic | IRO | ISO | p Value | IRN | ISN | p Value |
| Number | 76 | 96 | 17 | 131 | ||
| Gender (F/M) | 58/18 | 70/26 | 0.64 | 9/8 | 91/40 | 0.17 |
| Ethnicity (AA/EA) | 51/25 | 58/38 | 0.39 | 8/9 | 72/59 | 0.54 |
| Age (year) | 44.0±12.1 | 44.0±10.6 | 0.97 | 42.5±7.00 | 46.2±9.42 | 0.11 |
| BMI (kg/m2) | 36.7±6.86 | 35.1±5.26 | 0.04 | 26.4±2.23 | 24.2±2.89 | 0.003 |
| HOMA-IR | 3.51±1.60 | 1.49±0.83 | <0.0001 | 3.35±1.58 | 1.09±0.10 | <0.0001 |
| Si-clamp | 0.058±0.025 | 0.138±0.048 | <0.0001 | 0.065±0.019 | 0.176±0.056 | <0.0001 |
| FPG (mg/dL) | 93.3±6.47 | 92.7±7.57 | 0.60 | 93.6±5.78 | 90.7±6.29 | 0.08 |
| 2hrPG (mg/dL) | 128±27.2 | 125±24.2 | 0.42 | 129±23.8 | 121±26.8 | 0.19 |
| HbA1c (%) | 5.59±0.56 | 5.64±0.44 | 0.24 | 5.58±0.42 | 5.51±0.40 | 0.22 |
| Food habits score | 2.64±0.50 | 2.57±0.44 | 0.36 | 2.70±0.46 | 2.54±0.55 | 0.26 |
| Physical activity (Met-hour/week) | 18.0±42.2 | 13.8±19.6 | 0.43 | 13.7±21.3 | 22.5±35.1 | 0.32 |
To convert the values for glucose to millimoles per liter, multiply by 0.0555.
2hrPG, 2-hour plasma glucose during 75 g oral glucose tolerance test; AA, African American; EA, European American; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HOMA-IR, homeostasis model of insulin resistance; IRN, insulin-resistant non-obese; IRO, insulin-resistant obese; ISN, insulin-sensitive non-obese; ISO, insulin-sensitive obese; Si-clamp, insulin sensitivity by hyperinsulinemic euglycemic clamp expressed as µmol/kg fat-free mass/min/pmol/L .