Table 3.
Variable | All patients | Mild | Severe | ||||
Adjusted OR | p Value | Adjusted OR | p Value | Adjusted OR | p Value | ||
Severity (vs. mild*) |
Moderate | 1.08 (0.69,1.69) | 0.0002 | N/A | |||
Severe | 1.86 (1.39, 2.50) | ||||||
Gender (male vs female*) |
1.16 (0.94, 1.43) | 0.16 | 1.24 (0.97, 1.58) | 0.085 | † | ||
Age (≥65 vs <65*) |
† | † | 0.57 (0.33, 1.00) | 0.049 | |||
BCVA in worse eye (visual impairment vs normal*) |
2.38 (1.84, 3.08) | <0.0001 | 2.42 (1.76, 3.32) | <0.0001 | 2.21 (1.34, 3.64) | 0.0018 | |
Insurance (vs no insurance*) |
Medicaid | 1.04 (0.75, 1.43) | 0.15 | 0.92 (0.63, 1.35) | 0.058* | 1.26 (0.65, 2.45) | 0.11* |
Medicare | 1.39 (1.00, 1.94) | 1.25 (0.84, 1.86) | 2.10 (1.04, 4.27) | ||||
Medicaid and Medicare | 0.79 (0.37, 1.70) | 0.71 (0.29, 1.72) | 1.82 (0.23, 14.3) | ||||
Private/other/Vision | 1.01 (0.74, 1.37) | 0.76 (0.52, 1.10) | 2.10 (1.15, 3.86) | ||||
HbA1C in chart (yes vs no*) |
1.74 (1.37, 2.21) | <0.0001 | 1.98 (1.51, 2.60) | <0.0001 | † | ||
Blood sugar in chart (yes vs no*) |
1.82 (1.45, 2.29) | <0.0001 | 1.89 (1.43, 2.49) | <0.0001 | 2.01 (1.25, 3.22) | 0.0038 | |
Current smoking status (smoker vs no*) | 0.54 (0.41, 0.71) | <0.0001 | 0.54 (0.39, 0.73) | <0.0001 | † | ||
Medications (mental health) (yes vs no*) | † | † | 0.48 (0.20, 1.12) | 0.089 | |||
Wears glasses (yes vs no*) |
† | 1.21 (0.93, 1.59) | 0.16 | † | |||
Cataract (yes vs no*) |
1.53 (1.16, 2.01) | 0.0023 | 1.50 (1.09, 2.05) | 0.012 | † | ||
Glaucoma (yes vs no*) |
1.45 (1.04, 2.03) | 0.029 | 1.54 (1.04, 2.28) | 0.032 | † | ||
Non-diabetic retinal disease (yes vs no*) | 3.77 (2.57, 5.51) | <0.0001 | 5.77 (3.41, 9.78) | <0.0001 | 1.95 (1.07, 3.57) | 0.030 | |
Other ocular comorbidity (yes vs no*) | 1.52 (1.22, 1.89) | 0.0001 | 1.46 (1.13, 1.87) | 0.0032 | 1.61 (0.97, 2.67) | 0.063 |
*Reference group.
†Removed from final model via backwards elimination (p>0.2).
BCVA, best-corrected visual acuity; DFE, dilated fundus exam; HbA1c, hemoglobin A1c.