Table 1.

Patient cumulative laboratory results. Results exhibiting interference are shaded.

Assaya/units (reference range)	20/10/2011	23/11/2011	16/2/2012	22/5/2012	18/6/2012	25/1/2013	21/11/2013	19/2/2015	19 /2/2015 (HCU lab)b
TSH – µU/mL (0.34–5.60)	16.97**	17.73**	21.33**	26.91**	35.97**	14.90**	8.36*	10.23*	**0.05 (0.55–4.78)
fT4 – ng/dL (0.58–1.64)	0.93	0.93	0.83	0.96	1.19	1.35	1.18	0.84	1.19 (0.89–1.76)
fT3 – pg/mL (2.39–4.01)						4.44*		3.22	3.19 (2.3–4.2)
Ab. TPO – U/mL (0–4)		0.6	0.7			0.3		0.7	11.98 (0–100)
Ab. Tg – U/mL (0–9)						0.6		1.5	4.47 (0–138)
LH – mU/mL (1.26–10.05)						290.62**		128.54**	4.88 (0.8–7.6)
FSH – mU/mL (1.27–19.26)						87.52**		60.35**	2.16 (1.5–14)
Prolactin – ng/mL (2.64–13.3)						75.27**	54.12**	45.37**	8.96 (2.5–17)
Oestradiol – pg/mL (11–44)						31		19	43 (<15–56)
ACTH – pg/mL (5–46)					583**	396**	209**	165**	143**
Cortisol – µg/dL (5.0–25.0)					15.98	12.75	11.65	5.09	*4.06 (5–25)
GH – ng/mL (0.15–3.00)								0.42	0.44
IGF-1 – ng/mL (115–307)						322*		403*	244
Testosterone – ng/mL (1.75–7.81)						4.82	4.22	3.81	**0.41 (1.6–7.26)
Free testosterone – pg/mL (2.60–9.79)								4.56	8.48 (4.25–30.37)
SHBG – nmol/L (13.5–71.4)								41.7	45.3 (10–57)
Glycoprotein hormone alpha-subunit – mU/mL								<0.3 (0–1.6)

X*: above the upper reference limit. X**: well above the upper reference limit. *X: below the low reference limit. **X: well below the low reference limit.

^aTSH: thyrotropin; fT4: free thyroxine; fT3; free triiodothyronine; Ab. TPO: anti-peroxidase antibodies; Ab. Tg: anti-thyroglobulin antibodies; LH: luteinising hormone; FSH: follicular stimulating hormone; ACTH: adrenocorticotropic hormone; IGF-1: insulin-like growth factor 1; GH: somatotropin; SHBG: sex hormone-binding globulin.

^bThe results obtained in HCU laboratory are accompanied by their reference values when the analytical methods employed were different from those used at our laboratory.