Table 1. Echocardiography of 8–11 weeks old wildtype and Rbm38 -/- mice.
Wildtype (n = 15) | Rbm38 -/- (n = 13) | p-value | |
---|---|---|---|
LVID;d | 3.94 ± 0.04 | 3.89 ± 0.04 | 0.46 |
LVID;s | 2.83 ± 0.04 | 2.71 ± 0.07 | 0.07 |
LVAW;d | 1.04 ± 0.03 | 1.11 ± 0.13 | 0.13 |
LVAW;s | 1.39 ± 0.03 | 1.51 ± 0.04 | 0.03 |
LVPW;d | 0.74 ± 0.03 | 0.77 ± 0.03 | 0.40 |
LVPW;s | 1.00 ± 0.03 | 1.01 ± 0.03 | 0.84 |
%FS | 28.21 ± 0.59 | 30.34 ± 0.96 | 0.06 |
%EF | 55.06 ± 0.91 | 58.20 ± 1.37 | 0.06 |
LVID: left ventricular internal diameter, LVAW: left ventricular anterior wall thickness, LVPW: left ventricular posterior wall thickness, %FS: percentage fractional shortening, %EF: percentage ejection fraction, ;d is during diastole, and ;s is during systole. Data are presented as mean ± sem, and were tested with a 2-tailed Student’s t-test.