Table 1. Table representing the genetic alterations from tumor biopsy.

Ala: Alanine; Arg: Arginine; Asp: Asparagine;Cys: Cysteine; Gly: Glycine; His: Histidine; Leu: Leucine; Phe: Phenylalanine; Pro: Proline; Ser: Serine; Thr: Threonine; Trp: Tryptophan; Tyr: Tyrosine; Val: Valine. ATM: Serine-protein kinase ATM; CCND1: G1/S-specific cyclin-D1; EMSY: BRCA2-interacting transcriptional repressor EMSY; FANCF: Fanconi anemia group F protein; FGF19: Fibroblast growth factor 19; FGF3: Fibroblast growth factor 3; FGF4: Fibroblast growth factor 4; FOXP1: Forkhead box protein P1; GPR124: G-protein coupled receptor 124; MLL3: lysine methyltransferase 2C; MYST3: MYST histone acetyltransferase (monocytic leukemia) 3; PALB2: partner and localizer of BRCA2; PIK3CA: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; TP53: Tumor Protein P53; ZNF703: Zinc finger protein 703

Gene	Effect (amino acid change)	Gene	Effect   (copy number change, rearrangement and insertion)
PIK3CA	p.His1047Leu	PIK3CA	Amplification
TP53	p.Arg248Trp	CCND1	Amplification
ATM	p.Ser1691Arg	FGF19	Amplification
FANCF	p.Ala186Val	FGF4	Amplification
FOXP1	p.His520Tyr	EMSY	Amplification
GPR124	p.Ser1276Arg	FGF3	Amplification
MLL3	p.Ser836Phe	PALB2	Rearrangement exon 5 -- truncation
MYST3	p.Ala1521Ser	ZNF703	His402_Asp403>ProThrHisLeuGlyGlySerSerCysSerThrCysSerAlaHisAsp