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. 2017 Apr 19;20(8):634–643. doi: 10.1093/ijnp/pyx026

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© The Author 2017. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Short-interval afferent inhibition (SAI) before and after drug administration. The figure displays SAI under different conditions: single-dose placebo (sPLC), single-dose reboxetine (RBX), chronic reboxetine+placebo medication at the day of experiment (cPLC), and chronic reboxetine+reboxetine at the day of experiment (cRBX). After application of both, single dose and chronic RBX, SAI was significantly decreased for ISI 20. Compared with the sPLC condition, in the cPLC condition, SAI was significantly reduced at ISI 20 milliseconds. Asterisks indicate significant differences of the MEP amplitude between before and after drug intake (Student’s t test, P<.05). The hash symbol indicates significant differences of the MEP amplitude between sPLC and cPLC after drug intake. Vertical bars depict SEM.