Table 1.
Repeated-Measures ANOVA Results
| Measurement | Parameters | df | F-value | P value |
|---|---|---|---|---|
| 1-mV intensity | Drug | 3 | 0.358 | .784 |
| Time | 1 | 0.541 | .483 | |
| Drug x time | 3 | 1.583 | .220 | |
| AMT | Drug | 3 | 2.663 | .071 |
| Time | 1 | 1.583 | .224 | |
| Drug x time | 3 | 1.254 | .112 | |
| RMT | Drug | 3 | 0.534 | .663 |
| Time | 1 | 1.254 | .295 | |
| Drug x time | 3 | 0.544 | .486 | |
| I-O curve | Drug | 3 | 4.916 | .006 |
| Time | 1 | 3.104 | .104 | |
| Intensity | 3 | 123.338 | <.001 | |
| Drug x time | 3 | 1.762 | .174 | |
| Drug x intensity | 9 | 4.869 | <.001 | |
| Time x intensity | 3 | 1.230 | .314 | |
| Drug x time x intensity | 9 | 1.159 | .330 | |
| SICI-ICF | Drug | 3 | 8.423 | <.001 |
| Time | 1 | 9.489 | .01 | |
| ISI | 4 | 5.171 | .002 | |
| Drug x time | 3 | 13.770 | <.001 | |
| Drug x ISI | 12 | 4.481 | <.001 | |
| Time x ISI | 4 | 5.831 | .001 | |
| Drug x time x ISI | 12 | 5.267 | .001 | |
| I-wave facilitation | Drug | 3 | 3.254 | .034 |
| Time | 1 | 2.308 | .157 | |
| ISI | 9 | 14.340 | <.001 | |
| Drug x time | 3 | 1.820 | .163 | |
| Drug x ISI | 27 | 2.233 | <.001 | |
| Time x ISI | 9 | 0.863 | .561 | |
| Drug x time x ISI | 27 | 1.767 | .012 | |
| SAI | Drug | 3 | 19.886 | <.001 |
| Time | 1 | 14.218 | .003 | |
| ISI | 1 | 32.029 | <.001 | |
| Drug x time | 3 | 0.650 | .558 | |
| Drug x ISI | 3 | 1.753 | .175 | |
| Time x ISI | 1 | 1.497 | .247 | |
| Drug x time x ISI | 3 | 0.440 | .726 |
Abbreviations: AMT, active motor threshold; I-O curve, input-output curve; SICI-ICF, short-latency intracortical inhibition and intracortical facilitation; RMT, resting motor threshold; SAI, short-interval afferent inhibition.
*Significant results at P < .05, d.f., degrees of freedom.