Table 3.

OR for being in the symptom profiles compared to the “no symptoms” profile according to age, sex, and chronic disease

Profile	No symptoms	Few, mixed symptoms	Headache	MS	GI	Fatigue	Pulmonary	MS + GS	MS + GI + GS	All symptoms
Age
OR, per year	1	1.14	0.92	1.03	0.98	0.97	1.05	1.04	1.02	1.03
(95% CI)	(Ref.)	(1.11–1.16)	(0.91–0.93)	(1.03–1.04)	(0.97–0.99)	(0.96–0.98)	(1.04–1.06)	(1.03–1.04)	(1.01–1.03)	(1.02–1.05)
Sex
Women vs men, OR	1	0.9	7.3	1.8	2.6	2.0	0.7	2.1	3.5	1.3
(95% CI)	(Ref.)	(1.9–2.9)	(5.1–10.3)	(1.6–2.0)	(2.1–3.2)	(1.5–2.6)	(0.6–0.9)	(1.7–2.5)	(2.6–4.8)	(0.9–1.9)
Chronic disease
Musculoskeletal, OR	1	8.8	0.9	48.9	1.5	1.2	3.2	17.5	9.5	11.5
(95% CI)	(Ref.)	(6.9–11.3)	(0.7–1.2)	(34.0–70.3)	(1.2–1.9)	(0.9–1.6)	(2.6–4.1)	(13.5–22.8)	(7.2–12.4)	(7.1–18.5)
Cardio-metabolic, OR	1	6.5	0.4	2.5	1.2	1.7	6.4	5.1	3.5	8.1
(95% CI)	(Ref.)	(5.3–7.9)	(0.2–0.6)	(2.2–2.8)	(1.0–1.6)	(1.2–2.3)	(5.0–8.1)	(4.2–6.1)	(2.7–4.4)	(5.3–12.3)
Mental, OR	1	5.8	5.2	3.5	6.8	24.3	7.7	19.9	14.1	33.8
(95% CI)	(Ref.)	(4.5–7.5)	(4.2–6.5)	(2.9–4.2)	(5.4–8.5)	(18.9–31.2)	(5.8–10.1)	(16.3–24.4)	(10.9–18.2)	(22.0–51.9)
Pulmonary, OR	1	2.7	1.9	2.2	1.7	0.7	39.7	5.2	4.6	14.7
(95% CI)	(Ref.)	(2.1–3.5)	(1.5–2.5)	(1.8–2.6)	(1.2–2.3)	(0.3–1.7)	(28.9–54.6)	(4.2–6.5)	(3.4–6.1)	(9.8–22.2)

Notes: The model includes direct effects between rapid heartbeat and chest pain and between urinary incontinence and urinary retention. N=35,188–36,163. GS includes headache, tiredness, and sleeplessness.

Abbreviations: GI, gastrointestinal; GS, general symptoms; MS, musculoskeletal; OR, odds ratio; Ref., reference profile.