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. 2017 Aug 25;11:58. doi: 10.3389/fncir.2017.00058

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Copyright © 2017 Hudson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Possible dependencies of attractors on anesthetic concentration. The brain appears to engage in stereotyped behavior when a given anesthetic concentration is delivered to the brain, suggesting that a given drug and dose establish an attractor for the brain, here imagined as a particle on a potential surface that is constantly disturbed by noise, indicated by small arrows, as in Figure 1C. The way in which these attractors change as the anesthetic concentration changes has not been well characterized. (A) The attractor could move continuously as the anesthetic is increased. (B) The width of the well, which defines it’s stability, as well as its location, could shift. Or (C) the nature of the attractor landscape could qualitatively change, with the appearance of a new attractor that could coexist with the original attractor for some anesthetic concentrations.