Table 2.
Cardiac Echo Measurements.
| Control | DOCA-salt rats | Serelaxin treated DOCA-salt rats | |
|---|---|---|---|
| IVSd (mm) | 1.28 ± 0.03 | 1.53 ± 0.06* | 1.33 ± 0.05** |
| IVSs (mm) | 2.00 ± 0.05 | 2.22 ± 0.07* | 2.12 ± 0.09 |
| LVIDd (mm) | 7.74 ± 0.17 | 8.58 ± 0.15* | 8.22 ± 0.17 |
| LVIDs (mm) | 4.61 ± 0.18 | 5.42 ± 0.28* | 4.79 ± 0.24 |
| IVPWd (mm) | 1.28 ± 0.03 | 1.52 ± 0.06* | 1.32 ± 0.05** |
| LVPWs (mm) | 1.99 ± 0.04 | 2.23 ± 0.07* | 2.11 ± 0.09 |
| Heart Rate (BPM) | 373.15 ± 6.31 | 354.36 ± 7.25 | 405.30 ± 12.04** |
| LV Vold (ul) | 321.65 ± 16.35 | 403.55 ± 15.46* | 367.36 ± 16.90 |
| LV Vols (ul) | 99.07 ± 9.60 | 145.22 ± 16.56* | 108.83 ± 12.97 |
| Ejection fraction (%) | 69.52 ± 1.58 | 64.00 ± 3.83 | 70.79 ± 2.32 |
All values shown represent the mean ± SEM. N = 6 rats per group. IVSd (Interventricular septal end diastole), IVSs (Interventricular septal end systole), LVIDd (Left ventricular internal diameter end diastole), LVIDs (Left ventricular internal diameter end systole), LVPWd (Left ventricular posterior wall end diastole), LVPWs (Left ventricular posterior wall end systole), LV Vold, (LV diastolic volume), LV Vols (LV systolic volume). Significance: *P < 0.05 vs Control rats; **P < 0.05 vs DOCA-salt rats.