Table 2.

The statistic results of these predictive models (5-fold cross validation and test set validation).

Uniprot_ID	Gene name	5-fold cross validation				Test set validation
		AUC	ACC	SE	SP	AUC	ACC	SE	SP
P08908	HTR1A	0.950	0.904	0.884	0.924	0.961	0.921	0.911	0.931
Q9Y5N1	HRH3	0.985	0.955	0.944	0.967	0.991	0.970	0.967	0.973
P50406	HTR6	0.969	0.930	0.918	0.942	0.986	0.953	0.932	0.974
P22303	ACHE	0.892	0.845	0.818	0.871	0.944	0.903	0.886	0.922
Q99720	SIGMAR1	0.967	0.918	0.897	0.938	0.979	0.949	0.944	0.955
P11229	CHRM1	0.864	0.808	0.798	0.818	0.938	0.882	0.882	0.883
P49841	GSK3B	0.892	0.821	0.786	0.856	0.963	0.903	0.902	0.905
P06276	BCHE	0.879	0.820	0.797	0.842	0.926	0.855	0.862	0.848
P56817	BACE1	0.961	0.930	0.919	0.942	0.971	0.942	0.951	0.934
P27338	MAOB	0.888	0.826	0.809	0.842	0.941	0.877	0.860	0.895
P36544	CHRNA7	0.875	0.824	0.791	0.857	0.916	0.846	0.792	0.899
Q07343	PDE4B	0.957	0.914	0.884	0.945	0.974	0.942	0.953	0.930
P27815	PDE4A	0.951	0.917	0.911	0.924	0.962	0.922	0.910	0.934
Q13639	HTR4	0.963	0.943	0.921	0.965	0.976	0.950	0.920	0.977
P46098	HTR3A	0.894	0.853	0.810	0.896	0.928	0.892	0.833	0.949
Q96BI3	APH1B	0.942	0.899	0.917	0.882	0.973	0.948	0.963	0.935
P05067	APP	0.973	0.915	0.881	0.950	0.944	0.912	0.867	0.961
Q9NZ42	PSENEN	0.945	0.924	0.946	0.903	0.951	0.914	0.953	0.880
Q8WW43	APH1B	0.937	0.920	0.938	0.902	0.952	0.935	0.924	0.944