Table 3.
The IC50 values of 13 compounds under study.
| Compound | S-1 | S-2 | S-3 | S-4 | S-5 | S-6 | S-7 | S-8 | S-9 | S-10 | S-11 | S-12 | S-13 | Z-factor | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 (μM) | BACE1 | 70.89 | 17.20 | 2.75 | 81.93 | 7.58 | 20.70 | 3.97 | 0.75 | 4.32 | 3.40 | 2.27 | 2.82 | 2.72 | 0.93 | 
| MAO-B | –a | 15.74 | 11.72 | 13.89 | 2.91 | 8.81 | 23.17 | 3.62 | 18.21 | 10.24 | –a | 3.52 | 3.42 | 0.89 | 
The IC50 value cannot be calculated in the predetermined concentration range.