Table 2.

Statistics for sequence-read coverages and rare variants leading to the causal variants for rare genetic diseases in each patient.

	Captured regions	307 genes	211 genes	65 genes
Sum of reads on target regions	575 Mb	138 Mb	109 Mb	43 Mb
On target rates1	30%	7.20%	5.20%	2.20%
Length of target regions	3.7 Mb	1.3 Mb	0.9 Mb	0.35 Mb
Mean read depth2	161×	128×	120×	127×
Number of variants	NA	1186	762	271
Number of rare variants with probable deleterious effects	NA	8.6	6.2	3.4
Number of disease candidates	NA	3.6	2.7	1.8

¹[(Sum of reads on target regions)/(sum of all reads, 2.1 Gigabytes)] × 100. ²(Sum of reads on target regions)/(length of target regions).