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. 2017 Aug 29;7:9848. doi: 10.1038/s41598-017-10329-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Histopathological analysis of liver tissues from normal and HCV-infected tupaias at 41 wpi. Histopathological analysis was performed with H&E or silver staining. H&E staining images (upper panel) and silver staining images (lower panel) of liver tissues from (A) Normal tupaia #5, (B) Normal tupaia #38, (C) HCV genotype 1a-infected tupaia #21, (D) HCV genotype 1b-infected tupaia #22, (E) HCV genotype 4a -infected tupaia #23, and (F) HCV genotype 2a -infected tupaia #24 have been shown. Black bars indicate 100 μm.