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. 2017 Aug 29;7:9808. doi: 10.1038/s41598-017-09622-2

Figure 1.

Figure 1

19F Cryogenic Radiofrequency Probe design and experimental setup. (A) Side view of the 19 F-CRP showing its geometry including external protective cylinder and an inner ceramic probe head that encloses the loop coil elements (not shown). The inner diameter dimension for the inner ceramic structure is shown in the cross-sectional view (right). (B) Three different experimental setups that were used to assess the 19 F-CRP quality. Shown are Setup 1 for the high concentration 19F phantom (upper panel), Setup 2 for the 19F nanoparticle phantoms (middle panel) and Setup 3 for the mouse brain phantom (lower panel). The dimension of the phantom setups are to scale with the dimensions of both 19 F-CRP and RT coil and an anatomic reference is shown on the right for comparison. The nanoparticles used in this study had the following physical characteristics: Z-average diameter = 164 nm, PdI = 0.06, z-Potential = 0.19 mV.