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. 2017 Aug 29;7:9695. doi: 10.1038/s41598-017-09069-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Optoacoustic temperature estimations in a tissue mimicking phantom. (a–c) Transverse and coronal maximum intensity projection (MIP) optoacoustic images reconstructed for three different time points during laser heating of the phantom; (d) The temperature increase estimated from the optoacoustic signal variations (dashed curves) as compared to the temperature increase measured with thermocouples (solid curves). The regions of interest considered for the estimation are marked in panel a; (e) Relative deviation of the F factor from the theoretical value as a function of the temperature increase.