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. 2017 Aug 29;7:9605. doi: 10.1038/s41598-017-09867-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Heterozygous tcf7l2 ^exI/+ adults have a reduced rate of caudal fin regeneration. (A) Bright field live images of unamputated and regenerating fins in wild type and tcf7l2 ^exI/+ after 72 hours post-amputation. The area of regeneration was determined and the original cut line was used to normalize fin size differences. (B) Graphic presentation of the regeneration rate in controls and tcf7l2 ^exI/+ mutant fish. Data were obtained from six fishes per genotype, repeated in 3 different experiments.