Table 2.
Univariate and multivariate Cox regression analyses of OS in 151 ccRCC patients.
| Covariates | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Age at surgery ( > 50 vs ≤ 50) | 1.034(0.484~2.211) | 0.930 | — | — |
| Sex (Male vs Female) | 1.174(0.530~2.603) | 0.692 | — | — |
| Tumor size ( > 4vs ≤ 4) | 3.437(1.623~7.280) | 0.001 | 1.563(0.629~3.879) | 0.336 |
| ECOG (1vs 0) | 6.259(2.918~13.426) | 0.000 | 4.762(2.093~10.836) | 0.000 |
| T stage (T2-4 vs T1) | 6.449(3.034~13.707) | 0.000 | 2.724(1.016~6.995) | 0.037 |
| ISUP grade (2 or 3-4 vs 1) | 2.944(1.561~5.552) | 0.001 | 2.077(1.103~3.910) | 0.024 |
| Necrosis (Present vs Absent) | 4.628(1.747~12.262) | 0.002 | 2.277(0.738~7.019) | 0.152 |
| COL23A1 expression (High vs Low) | 3.459(1.494~8.012) | 0.004 | 3.024(1.221~7.489) | 0.017 |
ISUP, International Society of Urological Pathology.