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. 2017 Aug 15;9(8):3586–3598.

Figure 6.

Figure 6

MiR-130a-3p inhibiting CXCL12 affected CNE-2Z cell cycle and promoted cell apoptosis. A: Flow cytometry (PI staining) results showed that si-CXCL12 group had the highest cells at G0/G1 stage, pcDNA3.1-CXCL12 had the lowest and miR-mimics+pcDNA3.1-CXCL12 had the middle cell count (student t-test, **P<0.01). B: Annexin V and PI staining detected CNE-2Z cells apoptosis. Si-CXCL12 group had the highest ratio, while pcDNA3.1-CXCL12 had the lowest ratio. MiR-mimics+pcDNA3.1-CXCL12 had a higher than pcDNA3.1-CXCL12 but lower than si-CXCL12 (student t-test, *P<0.05, ***P<0.001). Each assay was conducted in triplicate and repeated three times. The data show the mean of triplicate repeats ± s.e.m.