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. 2017 Aug 15;9(8):3599–3610.

Figure 5.

Figure 5

Effect ZEB1 inhibition on docetaxel sensitivity and cell apoptosis. To knock down ZEB1, PC-3-R cells overexpressing miR-204 were transfected with three synthetic ZEB1 siRNAs. ZEB1 levels were then measured via qPCR (A) and western blotting (B). Cell viability was measured after ZEB1 knockdown in PC-3-R cells overexpressing miR-204 and incubated with 20 nM docetaxel at varying incubation periods (C). Cell apoptosis rate were determined in PC-3-R cells overexpressing miR-204 transfected with ZEB1 siRNA or NC siRNA, followed by incubation with 20 nM docetaxel for 24 h using flow cytometry (D and E). *P<0.05, **P<0.01 vs. NC siRNA group.