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Curcumin inhibited tube formation through the inactivation of STAT3. NCI-H460 cells were transfected with pMXs-Stat3C or control plasmid for 48 hours before seeded in Matrigel and treated with curcumin (30 µmol/L) or vehicle for 6 hours. A. Representative photos of each groups. B. Statistical analysis of tube lengths. Data were presented as Mean ± SD. ***P < 0.001 vs. vehicle group, NS, no significant. All experiments were repeated at least three times.
