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. 2017 Aug 15;9(8):3676–3686.

Figure 2.

Figure 2

FL118 down-regulates the expression of drug-resistant proteins in the CSCs derived from A549 and H460. A: The expression of ERCC1and P-gp of A549 and H460 derived stem cells was examined by western blotting. GAPDH servers as the control. After treated with FL118 at 10 nM and 100 nM, the level of ERCC1and P-gp was downregulated over time. B: Quantitative RT-PCR was used to quantify ABCG2 mRNA expression in A549 and H460 derived stem cells after treating with FL118 for 48 h. *P<0.05. AS: A549 derived stem cells. HS: H460 derived stem cells.